Publications

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Matakatsu, MT, and Du, W. (2007) Direct control of proneural gene atonal by retinal determination factors during Drosophila eye development. Dev Biol. In press.

Sukhanova, M. Deb, D.K., Gordon, G.M., Matakatsu, MT, and Du, W. (2007) Proneural bHLH proteins and EGFR signaling coordinately regulate cell type specification and cdk inhibitor expression in Drosophila. MCB, 27, 2987-96.

Matakatsu, MT, Thomas, BJ, and Du, W. (2007) Mutation of the Apc1 homologue shattered disrupts normal eye development by disrupting G1 cell cycle arrest and progression through mitosis. Dev Biol. 309, 222-235. (Epub 2007 Jul 14).

Pogoriler J., Millen, K., Utset, M., and Du, W. (2006) Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development, Aug 30; [Epub ahead of print].

Shafaee, Z., Schmidt, H., Du, W., Posner, M., Weichselbaum, R., (2006) Cyclopamine increases the cytotoxic effects of taxol and radiation in Hedgehog expressing pancreatic cancer. Cancer Chemother Pharmacol. Mar 22; [Epub ahead of print]

Du, W. and Pogoriler, J (2006) Retinoblastoma Family Genes. Oncogene, 25, 5190-5200.

Lee, S., Zhang, X., Zhou, G., Shapino, J., Bao, J., Xu, J., Sun, M., Shi, R., Chen, J., Clark, T., Johnson, D., Tseng, C., Yang, H., Du, W., Wu, C., Wang, J., and Wang, S. (2005) Detecting novel low-abundant transcripts in Drosophila. RNA, 11, 939–946.

Duman-Scheel, M., Johnston, L., and Du, W. (2004) Repression of dMyc expression by Wingless promotes RBF-induced G1 arrest in the Presumptive Drosophila Wing Margin. PNAS, 101, 3857–3862.

Pogoriler, J and Du, W. (2004) Chk1 activation and the nuclear/cytoplasmic ratio. Developmental Cell, 7, 147-148.

Weng, L., Zhu, C., Xu, J. and Du, W. (2003) Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development. EMBO J., 22, 3865-3875.

Du, W. (2003) Endocycle and E2F-dependent transcriptional activation and repression. Cell Cycle, 2, 515-516.

Duman-Scheel, M., Weng, L., Xin, S., and Du, W. (2002) Hedgehog signaling controls cell proliferation and growth through upregulation of Cyclin D and Cyclin E. Nature, 417, 299-304.

Xin, S., Weng, L., Xu, J., and Du, W. (2002) The role of RBF in developmentally regulated cell proliferation in the eye disc and in Cyclin D/Cdk4 induced cellular growth. Development. 129, 1345-1356.

Xu, J., S. Xin, and W. Du. (2001). Drosophila Chk2 is required for DNA damage-mediated cell cycle arrest and apoptosis. FEBS Letters 508, 394-398.

Bosco G., Du, W., Orr-Weaver, T. (2001) DNA replication control through interaction of E2FRB and the origin recognition complex. Nature Cell Biology, 3, 289-295.

Du, W. (2000) Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain. Development. 127, 367-379.

Meyer, C.A., Jacobs, H.W., Datar, S.A., Du, W., Edgar, B.A., Christian F. Lehner, C.F. (2000) Drosophila Cdk4 stimulates growth and is dispensable for cell cycle progression. EMBO J. 19, 4533-4542.

Du, W., and Dyson, N. (1999) The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. EMBO J. 18, 916-925.

Du, W., Vidal, M., Xie, J., and Dyson, N. (1996) RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes & Dev. 10, 1206-1218

Du, W., Xie, J., and Dyson, N. (1996) Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J. 15, 3684-3692.

Du, W. and Maniatis, T. (1994) The high Mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms. Proc. Natl. Acad. Sci. USA 91. 11318-11322

Du, W., Thanos, D., and Maniatis, T. (1993) Mechanisms of Transcriptional Synergism between Distinct Virus Inducible Enhancer Elements. Cell 74, 887-898.

Du, W. and Maniatis, T. (1992) An ATF/CREB binding site is required for virus induction of the human interferon ß gene. Proc. Natl. Acad. Sci. USA 89. 2150-2154.