C. Bubici, S. Papa, C.G. Pham, F. Zazzeroni, G. Franzoso. 2004. NF-kB and JNK: an intricate affair. Cell Cycle, 3: 1524-1529.

C.G. Pham, C. Bubici, F. Zazzeroni, S. Papa, J. Jones, K. Alvarez, S. Jayawardena, E. De Smaele, R. Cong, C. Beaumont, F.M. Torti, S.V. Torti, G. Franzoso. 2004. Ferritin heavy chain upregulation by NF-kB inhibits TNFa-induced apoptosis by suppressing reactive oxygen species. Cell, 119: 529-542.
* Comments on Articles: 2004. SAGE KE, 46: nf102.

S. Papa, F. Zazzeroni, C.G. Pham, C. Bubici, G. Franzoso. 2004. Linking JNK signaling to NF-kB: a key to survival. J. Cell Sci., 117: 5197-5208.

B.C. Barnhart, P. Legembre, E. Pietras, C. Bubici, G. Franzoso, M.E. Peter. 2004. CD95 ligand induces motility and invasiveness of apoptosis resistant tumor cells. EMBO J., 23: 3175-3185.

S. Papa, F. Zazzeroni, C. Bubici, S. Jayawardena, C.G. Pham, K. Alvarez, S. Matsuda, D.U. Nguyen, A. H. Nelsbach, T. Melis, E. De Smaele, W.-J. Tang, L. D'Adamio, G. Franzoso. 2004. Gadd45b mediates the NF-kB suppression of JNK signaling by targeting MKK7/JNKK2. Nat. Cell Biol., 6: 146-153.
* Updates: 2004. Trends Immunol., 25: 402-405.
* Signaling Updates: 2004. AfCS Nature.

J.C. Lo, R.K. Chin, Y. Lee, H.-S. Kang, Y. Wang, J.V. Weinstock, T. Banks, C.F. Ware, G. Franzoso and Y.-X. Fu. 2003. Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues. J. Clin. Invest., 112: 1495-1504.

F. Zazzeroni, S. Papa, A. Algeciras-Schimnich, K. Alvarez, T. Melis, C. Bubici, N. Majewski, N. Hay, E. De Smaele, M. Peter, G. Franzoso. 2003. Gadd45b mediates the protective effects of CD40 co-stimulation against Fas-induced apoptosis. Blood, 102: 3270-3279.

N. Liu, S.M. Raja, F. Zazzeroni, S.S. Metkar, R. Shah, M. Zhang, Y. Wang, D. Broemme, W.A. Russin, J.C. Lee, M.E. Peter, C.J. Froelich, G. Franzoso and P.G. Ashton-Rickardt. 2003. NF-kB protects from the lysosomal pathway of cell death. EMBO J., 22: 5313-5322.

F. Zazzeroni, S. Papa, E. De Smaele, G. Franzoso. 2003. Cell survival and Gadd45-factor deficiency. Nature, 424: 742.

M.A. Medici, M.T. Sciortino, D. Perri, C. Amici, E. Avitable, M. Ciotti, E. Balestrieri, E. De Smaele, G. Franzoso and A. Mastino. 2003. Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: Role of nuclear factor-kB. J. Biol. Chem., 278: 36059-36067.

G. Franzoso, F. Zazzeroni, S. Papa. 2003. JNK: a killer on a transcriptional leash. Cell Death Differ., 10: 13-15.

R. Jin, E. De Smaele, F. Zazzeroni, D. U. Nguyen, S. Papa, J. Jones, C. Cox, C. Gelinas, G. Franzoso. 2002. Regulation of the gadd45b promoter by NF-kB. DNA Cell Biol., 21: 491-503.

C. Guiet, E. Silvestri, E. DeSmaele, G. Franzoso, and P. Vito. 2002. c-FLIP efficiently rescues TRAF2-/- cells from TNF-induced apoptosis. Cell Death Differ., 9: 138-144.

E. De Smaele, F. Zazzeroni, S. Papa, D. U. Nguyen, R. Jin, J. Jones, R. Cong, and G. Franzoso. 2001. Induction of gadd45b by NF-kB down-regulates pro-apoptotic JNK signaling. Nature, 414: 308-313.
* News and Views: 2001. Nature, 414: 265-266.
* Highlights: 2001. Nature Rev. Mol. Cell Biol., 2: 875.
* Hot Papers: 2003. The Scientist, 17: 32.

A. Leonardi, H. Ellinger-Ziegelbauer, G. Franzoso, K. Brown, and U. Siebenlist. 2000. Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. J. Biol. Chem., 275: 271-278.

B.F. Boyce, L. Xing, G. Franzoso, U. Siebenlist. 1999. Required and nonessential functions of nuclear factor-kB in bone cells. Bone, 25: 137-139.

D.C. St.Louis, J. Woodstock, G. Franzoso, P.J. Blair, L.M. Carlson, M. Murillo, M.R. Wells, A.J. Williams, D.S. Smoot, S. Kaushal, J.L. Grimes, D.M. Harlan, J.P. Chute, C.H. June, U. Siebenlist, and K.P. Lee. 1999. Evidence for distinct intracellular signaling pathways in CD34+ progenitor to dendritic cell differentiation from a human cell line model. J. Immunol., 162: 3237-3248.

A. Chariot, F. Princen, J. Gielen, M.P. Merville, G. Franzoso, K. Brown, U. Siebenlist, V. Bours. 1999. IkB-a enhances transactivation by the HOXB7 homeodomain-containing protein. J. Biol. Chem., 274: 5318-5325.

G. Franzoso, L. Carlson, L. Poljak, E.W. Shores, S. Epstein, A. Leonardi, A. Grinberg, T. Tran, T. Sharton-Kersten, M. Anver, P. Love, K. Brown, U. Siebenlist. 1998. Mice Deficient in NF-kB/p52 present with defects in humoral responses, germinal center reactions and splenic microarchitecture. J. Exp. Med., 187: 147-159.

G. Franzoso, L. Carlson, L. Xing, L. Poljak, E.W. Shores, K.D. Brown, A Leonardi, T. Tran, B.F. Boyce, U. Siebenlist. 1997. Requirement for NF-kB in osteoclast and B cell development. Genes Dev., 11: 3482-3496.

K. D. Brown, G. Franzoso, L. Baldi, L. Carlson, L. Mills, Y-C. Lin, S. Gerstberger, U. Siebenlist. 1997. The signal response of IkB-a is regulated by transferable N- and C-terminal domains. Mol. Cell. Biol., 17: 3021-3027.

G. Franzoso, L. Carlson, T. Sharton-Kersten, E.W. Shores, S. Epstein, A. Grinberg, T. Tran, E. Shacter, A. Leonardi, M. Anver, P. Love, A. Sher, U. Siebenlist. 1997. Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture and germinal center reactions. Immunity, 6: 479-490.

M. R. Ruocco, X. Chen, C. Ambrosino, E. Dragonetti, W. Liu, M. Mallardo, G. De Falco, C. Palmieri, G. Franzoso, I. Quinto, S. Venuta, G. Scala. 1996. Regulation of HIV-1 Long Terminal Repeats by interaction of C/EBP (NF-IL6) and NF-kB/Rel transcription factors. J. Biol. Chem., 271: 22479-22486.

G. Franzoso, L. Carlson, K. Brown, M. Daucher, P. Bressler and U. Siebenlist. 1996. Activation of the Serum Response Factor (SRF) by p65/NF-kB. EMBO J., 15: 3403-3412.

L. Baldi, K. Brown, G. Franzoso, U. Siebenlist. 1996. Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of IkB-a. J. Biol. Chem., 271: 376-379.

P.D. Drew, G. Franzoso, K.G. Becker, V. Bours, L.C. Carlson, U. Siebenlist, K. Ozato. 1995. Interferon Regulatory Factor-2 physically interacts with NF-kB and inhibits NF-kB induction of Major Histocompatibility Class I and b2-microglobulin gene expression in transfected human neuronal cells. J. Neuroimmunol., 63: 157-162.

P.D. Drew, G. Franzoso, K.G. Becker, V. Bours, L.C. Carlson, U. Siebenlist, K. Ozato. 1995. NF-kB and Interferon Regulatory Factor-1 physically interact and synergistically induce Major Histocompatibility Class I gene expression. J. Interf. Cytok. Res., 15: 1037-1045.

K. Brown, S. Gerstberger, L. Carlson, G. Franzoso, U. Siebenlist. 1995. Control of IkB-a proteolysis by site-specific signal-induced phosphorylation. Science, 267: 1485-1488.

T. Kanno, G. Franzoso, U. Siebenlist. 1994. Human T cell leukemia virus type Tax-protein-mediated activation of NF-kB from p100 (NF-kB2)-inhibited cytoplasmic reservoirs. Proc. Natl. Acad. Sci. (U.S.A.), 91: 12634-12638.

T. Kanno, K. Brown, G. Franzoso, U. Siebenlist. 1994. Kinetic analysis of Human T-cell Leukemia Virus type I Tax-mediated activation of NF-kB. Mol. Cell. Biol., 14: 6443-6451.

G. Franzoso, P. Biswas, G. Poli, L. Carlson, K. Brown, M. Tomita-Yamaguchi, A.S. Fauci, U. Siebenlist. 1994. A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the Nuclear Factor-kB subunit p65 in vitro and may impair Human Immunodeficiency Virus replication in these cells. J. Exp. Med.,180: 1445-1456.

U. Siebenlist, K. Brown, G. Franzoso. 1994. NF-kB: a mediator of pathogen and stress responses. In Inducible gene expression. Ed. P. Baeuerle. Publ. Birkhauser. p. 93-141.

U. Siebenlist, G. Franzoso, K. Brown. 1994. Structure, regulation and function of NF-kB. Annu. Rev. Cell Biol., 10: 405-455.

G. Franzoso, P.-C. Hu, G.A. Meloni, M.F. Barile. 1994. Immunoblot analyses of chimpanzee sera after infection and after immunization and challenge with Mycoplasma pneumoniae. Infect. Immun., 62: 1008-1014.

G. Franzoso, V. Bours, V. Azarenko, S. Park, M. Tomita-Yamaguchi, T. Kanno, K. Brown, U. Siebenlist. 1993. The oncoprotein Bcl-3 can facilitate NF-kB- mediated transactivation by removing inhibiting p50 homodimers from select kB sites. EMBO J., 12: 3893-3901.

J.H. Segars, T. Nagata, V. Bours, J.A. Medin, G. Franzoso, J.C.G. Blanco, P.D. Drew, K.G. Becker, J. An, T. Tang, D.A. Stephany, B. Neel, U. Siebenlist, K. Ozato. 1993. Retinoic acid induction of Major Histocompatibility Complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-kB (p50/p65) and Retinoic Acid Receptor b-Retinoid X Receptor b heterodimers. Mol. Cell. Biol.,13: 6157-6169.

D.S. Dimitrov, G. Franzoso, M. Salman, R. Blumenthal, M. Tarshis, M.F. Barile and S.Rottem. 1993. Mycoplasma fermentans (incognitus strain) cells are able to fuse with T-lymphocytes. Clin. Infect. Dis., 17: S305-S308.

G. Franzoso, P.-C. Hu, G.A. Meloni, M.F. Barile. 1993. The immunodominant 90 kilodalton protein is localized on the terminal tip structure of Mycoplasma pneumoniae. Infect. Immun., 61: 1523-1530.

K. Brown, S. Park, T. Kanno, G. Franzoso, U. Siebenlist. 1993. Mutual regulation of the transcriptional activator NF-kB and its inhibitor, IkB-a. Proc. Natl. Acad. Sci. (U.S.A.), 90: 2532-2536.

V. Bours, G. Franzoso*, V. Azarenko, S. Park, T. Kanno, K. Brown, U. Siebenlist. 1993. The oncoprotein Bcl-3 directly transactivates through kB motifs via association with DNA-binding p50B homodimers. Cell, 72: 729-739.
* G. Franzoso is joint first author

V. Bours, G. Franzoso, K. Brown, S. Park, V. Azarenko, M. Tomita-Yamaguchi, K. Kelly, U. Siebenlist. 1992. Lymphocyte activation and the family of NF-kB transcription factor complexes. Curr. Top. Microbiol. Immunol., 182: 411-420.

G. Franzoso, V. Bours, S. Park, M. Tomita-Yamaguchi, K. Kelly, U. Siebenlist. 1992. The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kB-mediated inhibition. Nature, 359: 339-342.

G. Franzoso, D.S. Dimitrov, R. Blumenthal, M.F. Barile and S. Rottem. 1992. Fusion of Mycoplasma fermentans, strain incognitus, with T-lymphocytes. F.E.B.S. Letters, 303: 251-254.