Assistant Professor,
Ben May Department for Cancer Research
Assistant Professor,
Institute for Genomics and Systems Biology
Fellow,
Institute for Genomics and Systems Biology
Committee on Cancer Biology
Ph.D. Texas A&M Alkek Institute of Biosciences and Technology, 2000
B.S. Indiana University, 1994
Richard B Jones, Ph.D.
Research / References / Lab Website
Newman, E.A., Muh, S.J., Hovhannisyan, R.H., Warzecha, C.C., Jones, R. B., McKeehan, W.L., and Carstens, R.P. (2006) Identification of RNA-binding proteins that regulate FGFR2 splicing through the use of sensitive and specific dual color fluorescence minigene assays. RNA. 12: 1129-1141.
Jones R. B., Gordus, A.G., Krall, J., MacBeath, G. (2006) A Quantitative Protein Interaction Network for the ErbB Receptors Using Protein Microarrays. Nature. 439(7073):168-74.
Luo Y., Cho H.H., Jones R. B., Jin C., McKeehan W. L. (2004) Improved Production of Recombinant Fibroblast Growth Factor 7 (FGF7/KGF) from Bacteria in High Magnesium Chloride. Protein Expression and Purification. 33:326-31.
Ye S., Luo Y., Lu W., Jones R. B., Linhardt R. J., Capila I., Toida T., Kan M., Pelletier H., McKeehan W. L. (2001) Structural Basis for Interaction of FGF-1, FGF-2, and FGF-7 with Different Heparan Sulfate Motifs. Biochemistry 40:14429-14439.
Jones R. B., Carstens R. P, Luo Y., McKeehan W. L. (2001) 5'- and 3'-terminal Nucleotides in the FGFR2 ISAR Splicing Element Core Have Overlapping Roles in Exon IIIb Activation and Exon IIIc Repression. Nucleic Acids Research. 29:3557-3565.
Jones, R. B., Wang, F., Luo, Y., Yu, C., Jin, C., Suzuki, T., Kan, M., McKeehan, W. L. (2001) The Nonsense-Mediated Decay Pathway and Mutually Exclusive Expression of Alternatively Spliced FGFR2IIIb and IIIc mRNAs. Journal of Biological Chemistry. 276:4158-4167.
Yu, C., Wang, F., Kan, M., Jin, C., Jones, R. B., Weinstein, M., Deng, C. X., McKeehan, W. L. (2000) Elevated Cholesterol Metabolism and Bile Acid Synthesis in Mice Lacking Membrane Tyrosine Kinase Receptor FGFR4. Journal of Biological Chemistry. 275:15482-15489.
Luo Y., Lu W., Mohamedali K. A., Jang J. H., Jones R. B., Gabriel J. L., Kan M., McKeehan W. L.(1998) The Glycine Box: a Determinant of Specificity for Fibroblast Growth Factor. Biochemistry 37:16506-16515.
Jasper, S. A., Jones, R. B., Mattern, J., Huffman, J. Todd, L. J. (1994) Palladium-Mediated Substitution Reactions of Polyhedral Borane Anions. Inorganic Chemistry 33:5620-5624.