The Ben May Department for Cancer Research | The University of Chicago

Appointments:

Professor,
Ben May Department for Cancer Research

Committee on Immunology

Committee on Cancer Biology

The Cancer Center

Education:

Diploma, University of Bayreuth, Germany, 1986

Ph.D., University of Bayreuth
Germany, 1988

Habilitation, University of Heidelberg
Germany, 1997

Contact:

Knapp Room R112

Voice: 773/ 702.4728
Fax: 773/ 702.3701

Email: mpeter@uchicago

Marcus E. Peter, Ph.D.
Research / References / Lab

Peter Citation Classics

The Peter lab has produced a number of citation classics.

Citations are as of May 29, 2008 (citations shown in bold denote first, co-first, senior or co-senior authorship).

a) "Summa classics"
1.	Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex CELL 85 (6): 817-827 JUN 14 1996 Times Cited: 2156
2.	Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways EMBO J 17 (6): 1675-1687 MAR 16 1998 Times Cited: 1643
3.	Kischkel FC, Hellbardt S, Behrmann I, et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor EMBO J 14 (22): 5579-5588 NOV 15 1995 Times Cited: 936
4.	Medema JP, Scaffidi C, Kischkel FC, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC) EMBO J 16 (10): 2794-2804 MAY 15 1997 Times Cited: 761
5.	Chinnaiyan AM, Tepper CG, Seldin MF, et al. FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis J BIOL CHEM 271 (9): 4961-4965 MAR 1 1996 Times Cited: 583
6.	Thome M, Schneider P, Hofmann K, et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors NATURE 386 (6624): 517-521 APR 3 1997 Times Cited: 574
7.	Schulze-Osthoff K, Ferrari D, Los M, et al. Apoptosis signaling by death receptors EUROPEAN JOURNAL OF BIOCHEMISTRY 254 (3): 439-459 JUN 15 1998 Times Cited: 537
8.	Scaffidi C, Schmitz I, Krammer PH, et al. The role of c-FLIP in modulation of CD95-induced apoptosis JOURNAL OF BIOLOGICAL CHEMISTRY 274 (3): 1541-1548 JAN 15 1999 Times Cited: 399
9.	Scaffidi C, Schmitz I, Zha JP, et al. Differential modulation of apoptosis sensitivity in CD95 type I and type II cells JOURNAL OF BIOLOGICAL CHEMISTRY 274 (32): 22532-22538 AUG 6 1999 Times Cited: 363

b) "mega classics"
10.	Peter ME, Krammer PH Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis CURRENT OPINION IN IMMUNOLOGY 10 (5): 545-551 OCT 1998 Times Cited: 292
11.	Peter ME, Krammer PH The CD95(APO-1/Fas) DISC and beyond CELL DEATH AND DIFFERENTIATION 10 (1): 26-35 JAN 2003 Times Cited: 275
12.	Scaffidi C, Medema JP, Krammer PH, et al. FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b JOURNAL OF BIOLOGICAL CHEMISTRY 272 (43): 26953-26958 OCT 24 1997 Times Cited: 260
13.	Krammer PH, Dhein J, Walczak H, et al. THE ROLE OF APO-1-MEDIATED APOPTOSIS IN THE IMMUNE-SYSTEM IMMUNOLOGICAL REVIEWS 142: 175-191 DEC 1994 Times Cited: 215
14.	Chang DW, Xing Z, Pan Y, et al. c-FLIPL is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis EMBO JOURNAL 21 (14): 3704-3714 JUL 15 2002 Times Cited: 181

c) "classics"
15.	Fulda S, Scaffidi C, Susin SA, et al. Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid JOURNAL OF BIOLOGICAL CHEMISTRY 273 (51): 33942-33948 DEC 18 1998 Times Cited: 143
16.	Fulda S, Friesen C, Los M, et al. Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors CANCER RESEARCH 57 (21): 4956-4964 NOV 1 1997 Times Cited: 142
17.	Algeciras-Schimnich A, Shen L, Barnhart BC, et al. Molecular ordering of the initial signaling events of CD95. MOL CELL BIOL. 2002 JAN;22(1):207-20. Times Cited: 137
18.	Peter ME, Kischkel FC, Scheuerpflug CG, et al. Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex EUROPEAN JOURNAL OF IMMUNOLOGY 27 (5): 1207-1212 MAR 1997 Times Cited: 137
19.	Scaffidi C, Kirchhoff S, Krammer PH, et al. Apoptosis signaling in lymphocytes CURRENT OPINION IN IMMUNOLOGY 11 (3): 277-285 JUN 1999 Times Cited: 131
20.	Barnhart BC, Alappat EC, Peter ME The CD95 type I/type II model SEMINARS IN IMMUNOLOGY 15 (3): 185-193 JUN 2003 Times Cited: 117
21.	Cahill MA, Peter ME, Kischkel FC, et al. CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases ONCOGENE 13 (10): 2087-2096 NOV 21 1996 Times Cited: 115
22.	Exley, M., Varticovski, L., Peter, M.E., Sancho, J. and Terhorst, C. Association of phosphoinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation J. BIOL. CHEM. 269, 15140-15146 1994 Times Cited: 108
23.	Kroemer G, El-Deiry W, Golstein P, et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death CELL DEATH AND DIFFERENTIATION 12: 1463-1467 2005 Times Cited: 100
24.	Peter ME, Heufelder AE, Hengartner MO Advances in apoptosis research PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (24): 12736-12737 NOV 25 1997 Times Cited: 100
25.	Martin DA, Zheng LX, Siegel RM, et al. Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (8): 4552-4557 APR 13 1999 Times Cited: 97
26.	Fulda S, Scaffidi C, Pietsch T, et al. Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells CELL DEATH AND DIFFERENTIATION 5 (10): 884-893 OCT 1998 Times Cited: 90
27.	Medema JP, Scaffidi C, Krammer PH, et al. Bcl-x(L) acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex JOURNAL OF BIOLOGICAL CHEMISTRY 273 (6): 3388-3393 FEB 6 1998 Times Cited: 81
28.	Stegh AH, Herrmann H, Lampel S, et al. Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis MOLECULAR AND CELLULAR BIOLOGY 20 (15): 5665-5679 AUG 2000 Times Cited: 80
29.	Willems F, Amraoui Z, Vanderheyde N, et al. Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide BLOOD 95 (11): 3478-3482 JUN 1 2000 Times Cited: 80
30.	Stegh AH, Schickling O, Ehret A, et al. DEDD, a novel death effector domain-containing protein, targeted to the nucleolus EMBO JOURNAL 17 (20): 5974-5986 OCT 15 1998 Times Cited: 79
31.	Peter ME, Kischkel FC, Hellbardt S, et al. CD95 (APO-1/Fas)-associating signalling proteins CELL DEATH AND DIFFERENTIATION 3 (2): 161-170 APR 1996 Times Cited: 77
32.	Medema JP, Toes REM, Scaffidi C, et al. Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis EUROPEAN JOURNAL OF IMMUNOLOGY 27 (12): 3492-3498 DEC 1997 Times Cited: 76

a) “summa classics” are cited more than 300 times;b) “mega classics” cited at least 150 times; and c) “classics” are cited at least 75 times.

Marcus E. Peter, Ph.D. Research / References / Lab

Peter Citation Classics

Marcus E. Peter, Ph.D.
Research / References / Lab