Selected Publications

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Jemc J, Rebay I. Identification of transcriptional targets of the dual-function transcription factor/phosphatase eyes absent. Dev Biol. 2007 Oct 15;310(2):416-29. Epub 2007 Jul 27.

Jemc J, Rebay I. The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem. 2007;76:513-38. Review.

Vivekanand P, Rebay I. Intersection of signal transduction pathways and development. Annu Rev Genet. 2006;40:139-57. Review.

Mutsuddi M, Chaffee B, Cassidy J, Silver SJ, Tootle TL, Rebay I. Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent. Genetics. 2005 Jun;170(2):687-95.

Rebay I, Silver SJ, Tootle TL. New vision from Eyes absent: transcription factors as enzymes. Trends Genet. 2005 Mar; 21(3):163-71. Review.

Tootle TL, Rebay I. Post-translational modifications influence transcription factor activity:a view from the ETS superfamily. Bioessays. 2005 Mar;27(3):285-98. Review.

Siver SJ, Rebay I. Signaling circuitries in development: insights from the retinal determination gene network. Development. 2005 Jan;132(1):3-13. Review.

Vivekanand P, Tootle TL, Rebay I. MAE, a dual regulator of the EGFR signaling pathway, is a target of the Ets transcription factors PNT and YAN. Mech. Dev. 2004 Dec;121(12):1469-79.

Qiao F, Song H, Kim CA, Sawaya MR, Hunter JB, Gingery M, Rebay I, Courey AJ, Bowie JU. Derepression by depolymerization; structural insights into the regulation of YAN by MAE. Cell. 2004 Jul 23;118(2):163-73.

Tootle TL, Siver SJ, Davies EL, Newman V, Latek RR, Mills IA, Selengut JD, Parlikar BE, Rebay I. The transcription factor Eyes absent is a protein tyrosine phosphatase. Nature. 2003 Nov 20;426(6964):299-302.

Silver SJ, Davies EL, Doyon L, Rebay I. Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network. Mol. Cell Biol. 2003 Sep;23(17):5989-99.

Tootle TL, Lee PS, Rebay I. CRM1-mediated nuclear export and regulated activity of the Receptor Tyrosine Kinase antagonist YAN require specific interactions with MAE. Development. 2003 Mar;130(5):845-57.

Hsiao FC, Williams A, Davies EL, Rebay I. Related Articles, Links Eyes absent mediates cross-talk between retinal determination genes and the receptor tyrosine kinase signaling pathway. Dev Cell. 2001 Jul;1(1):51-61.